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- Xyrem: Uses, Dosage, Side Effects, Warnings - Drugs. com
Xyrem’s mechanism of action for narcolepsy is thought to involve binding to GABA B and GHB receptors to enhance deep sleep at night, which helps to reduce EDS The exact way Xyrem works is unknown (see How does Xyrem work for narcolepsy?) Xyrem belongs to the class of medicines known as central nervous system (CNS) depressants
- Oxybate Treatment for Cataplexy and EDS in Narcolepsy |XYREM®
XYREM® (sodium oxybate) is approved for use in adults and children ages 7 and older to help treat cataplexy and EDS in narcolepsy See XYREM® prescribing information BOXED Warning about serious side effects, CNS depression, misuse and abuse
- Xyrem: Side effects, use for narcolepsy, dosage, and more
Xyrem and obstructive sleep apnea Clinical trials showed that for people with obstructive sleep apnea who took 9 g of Xyrem each night, there was no increase in how severe their sleep apnea was
- Effects of Oxybate on Sleep, Sleep Architecture, and . . .
Sleep disturbances in narcolepsy encompass self-reported sleep quality, sleep architecture, and DNS DNS is associated with frequent sleep stage shifts and awakenings arousals on polysomnography Sodium oxybate (SXB; Xyrem ® ), dosed twice nightly, is approved to treat excessive daytime sleepiness and cataplexy in patients with narcolepsy
- Implications of Oxybate Dosing Regimen for Sleep, Sleep . . .
Narcolepsy is associated with disrupted nighttime sleep (DNS) Sodium oxybate (SXB; Xyrem®), administered twice nightly, is indicated for the treatment of cataplexy and excessive daytime sleepiness in patients 7 years or older with narcolepsy
- Sodium Oxybate (Xyrem) - Uses, Side Effects, and More
Find patient medical information for Sodium Oxybate (Xyrem) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings It can also cause sleep
- Xywav or Xyrem: What’s the Difference? - Sleep Review
For more than a decade and a half, Xyrem (sodium oxybate) has been prescribed to patients with narcolepsy who experience cataplexy or excessive daytime sleepiness It was the only US Food and Drug Administration (FDA)-approved therapy for the treatment of cataplexy (though sleep physicians also prescribe other drugs off-label to alleviate the
- Xyrem Patient Tips: 7 things you should know - Drugs. com
Xyrem may not be suitable for some people including those with a history of depression, anxiety, psychosis, aggression, high blood pressure, heart disease, or kidney problems Xyrem may also not be suitable for people with sleep apnea or sleep-related breathing disorders as Xyrem may increase the risk of severe apneas or oxygen desaturation
- Xyrem (Sodium Oxybate): Side Effects, Uses, Dosage . . . - RxList
* For patients who sleep more than 8 hours per night, the first dose of Xyrem may be given at bedtime or after an initial  period of sleep **If Xyrem is used in patients 7 years of age and older who weigh less than 20 kg, a lower starting dosage, lower maximum weekly dosage increases, and lower total maximum nightly dosage should be considered
- How Xyrem Works For Narcolepsy And More - Walrus Health
Having the appropriate amount of REM sleep is also strongly related to next-day wakefulness Many studies show that a decrease in REM sleep is linked to grogginess and daytime sleepiness The major benefit of Xyrem is thought to be that it induces REM sleep However, the drug may work by additional mechanisms we don't completely understand
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