METTL7B Is Required for Cancer Cell Proliferation and . . . - Frontiers Here, we report evidence showing that one member of the mammalian methyltransferase-like family (METTL), METTL7B, is a potential molecular target for treatment of non-small cell lung cancer (NSCLC) METTL7B expression was elevated in the majority of NSCLC comparing to normal tissues
Thiol methyltransferase METTL7B coordinates lipid metabolism and . . . Dysregulated lipid metabolism drives cancer progression, yet the molecular mechanisms linking lipid accumulation to pancreatic cancer remain poorly understood Here, we identify methyltransferase-like 7B (METTL7B) as a key regulator of lipid metabolism and tumor progression in pancreatic cancer
Targeting METTL3 reprograms the tumor microenvironment to improve . . . Hence, it remains elusive whether and how METTL3 regulates TME and immunotherapy response in lung cancer Here, we utilize subcutaneous, orthotopic, and genetically engineered mouse models (GEMM) of lung cancer to characterize METTL3 regulation of TME and response to immunotherapy in vivo